Cargando…
Human Plasma-Derived 3D Cultures Model Breast Cancer Treatment Responses and Predict Clinically Effective Drug Treatment Concentrations
Lack of efficacy and a low overall success rate of phase I-II clinical trials are the most common failures when it comes to advancing cancer treatment. Current drug sensitivity screenings present several challenges including differences in cell growth rates, the inconsistent use of drug metrics, and...
Autores principales: | Calar, Kristin, Plesselova, Simona, Bhattacharya, Somshuvra, Jorgensen, Megan, de la Puente, Pilar |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407241/ https://www.ncbi.nlm.nih.gov/pubmed/32610529 http://dx.doi.org/10.3390/cancers12071722 |
Ejemplares similares
-
Mimicking tumor hypoxia and tumor-immune interactions employing three-dimensional in vitro models
por: Bhattacharya, Somshuvra, et al.
Publicado: (2020) -
Reduction of Metastasis via Epigenetic Modulation in a Murine Model of Metastatic Triple Negative Breast Cancer (TNBC)
por: Zylla, Jessica L. S., et al.
Publicado: (2022) -
Bioengineering the Oxygen-Deprived Tumor Microenvironment Within a Three-Dimensional Platform for Studying Tumor-Immune Interactions
por: Bhattacharya, Somshuvra, et al.
Publicado: (2020) -
Analysis of Dual Class I Histone Deacetylase and Lysine Demethylase Inhibitor Domatinostat (4SC-202) on Growth and Cellular and Genomic Landscape of Atypical Teratoid/Rhabdoid
por: Hoffman, Mariah M., et al.
Publicado: (2020) -
The WNK1–ERK5 route plays a pathophysiological role in ovarian cancer and limits therapeutic efficacy of trametinib
por: Sánchez‐Fdez, Adrián, et al.
Publicado: (2023)