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IL-6 Trans-Signaling in the Brain Influences the Metabolic Phenotype of the 3xTg-AD Mouse Model of Alzheimer’s Disease

Alzheimer’s disease (AD) is a neurodegenerative disorder that causes the most prevalent dementia in the elderly people. Obesity and insulin resistance, which may cause major health problems per se, are risk factors for AD, and cytokines such as interleukin-6 (IL-6) have a role in these conditions. I...

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Detalles Bibliográficos
Autores principales: Escrig, Anna, Molinero, Amalia, Méndez, Brenda, Giralt, Mercedes, Comes, Gemma, Sanchis, Paula, Fernández-Gayol, Olaya, Giménez-Llort, Lydia, Becker-Pauly, Christoph, Rose-John, Stefan, Hidalgo, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407279/
https://www.ncbi.nlm.nih.gov/pubmed/32630818
http://dx.doi.org/10.3390/cells9071605