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Engineering CD4+ T Cells to Enhance Cancer Immunity

This review presents key advances in combining T cell receptor (TCR) gene transfer to redirect T-cell specificity with gene engineering in order to enhance cancer-protective immune function. We discuss how emerging insights might be applied to CD4+ T cells. Although much attention has been paid to t...

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Detalles Bibliográficos
Autores principales: Sillito, Francesca, Holler, Angelika, Stauss, Hans J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407306/
https://www.ncbi.nlm.nih.gov/pubmed/32708397
http://dx.doi.org/10.3390/cells9071721