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CXCL14 Maintains hESC Self-Renewal through Binding to IGF-1R and Activation of the IGF-1R Pathway

Human embryonic stem cells (hESCs) have important roles in regenerative medicine, but only a few studies have investigated the cytokines secreted by hESCs. We screened and identified chemokine (C-X-C motif) ligand 14 (CXCL14), which plays crucial roles in hESC renewal. CXCL14, a C-X-C motif chemokin...

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Detalles Bibliográficos
Autores principales: Cheng, Chih-Lun, Yang, Shang-Chih, Lai, Chien-Ying, Wang, Cheng-Kai, Chang, Ching-Fang, Lin, Chun-Yu, Chen, Wei-Ju, Lin, Po-Yu, Wu, Han-Chung, Ma, Nianhan, Lu, Frank Leigh, Lu, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407311/
https://www.ncbi.nlm.nih.gov/pubmed/32708730
http://dx.doi.org/10.3390/cells9071706