The Intermediate Filament Synemin Regulates Non-Homologous End Joining in an ATM-Dependent Manner

The treatment resistance of cancer cells is a multifaceted process in which DNA repair emerged as a potential therapeutic target. DNA repair is predominantly conducted by nuclear events; yet, how extra-nuclear cues impact the DNA damage response is largely unknown. Here, using a high-throughput RNAi...

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Detalles Bibliográficos
Autores principales: Deville, Sara Sofia, Vehlow, Anne, Förster, Sarah, Dickreuter, Ellen, Borgmann, Kerstin, Cordes, Nils
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407367/
https://www.ncbi.nlm.nih.gov/pubmed/32605308
http://dx.doi.org/10.3390/cancers12071717

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407367/
https://www.ncbi.nlm.nih.gov/pubmed/32605308
http://dx.doi.org/10.3390/cancers12071717

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