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miR-7 Regulates GLP-1-Mediated Insulin Release by Targeting β-Arrestin 1

Glucagon-like peptide-1 (GLP-1) has been shown to potentiate glucose-stimulated insulin secretion binding GLP-1 receptor on pancreatic β cells. β-arrestin 1 (βARR1) is known to regulate the desensitization of GLP-1 receptor. Mounting evidence indicates that microRNAs (miRNAs, miRs) are fundamental i...

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Detalles Bibliográficos
Autores principales: Matarese, Alessandro, Gambardella, Jessica, Lombardi, Angela, Wang, Xujun, Santulli, Gaetano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407368/
https://www.ncbi.nlm.nih.gov/pubmed/32640511
http://dx.doi.org/10.3390/cells9071621