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On the Stability and Degradation Pathways of Venetoclax under Stress Conditions

Venetoclax is an orally bioavailable, B-cell lymphoma-2 (BCL-2) selective inhibitor, used for the treatment of various types of blood cancers, such as chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL). In this study we investigated the degradation of venetoclax under various st...

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Detalles Bibliográficos
Autores principales: Žigart, Nina, Črnugelj, Martin, Ilaš, Janez, Časar, Zdenko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407384/
https://www.ncbi.nlm.nih.gov/pubmed/32645956
http://dx.doi.org/10.3390/pharmaceutics12070639