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On the Stability and Degradation Pathways of Venetoclax under Stress Conditions
Venetoclax is an orally bioavailable, B-cell lymphoma-2 (BCL-2) selective inhibitor, used for the treatment of various types of blood cancers, such as chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL). In this study we investigated the degradation of venetoclax under various st...
Autores principales: | Žigart, Nina, Črnugelj, Martin, Ilaš, Janez, Časar, Zdenko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407384/ https://www.ncbi.nlm.nih.gov/pubmed/32645956 http://dx.doi.org/10.3390/pharmaceutics12070639 |
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