Water-Soluble closo-Docecaborate-Containing Pteroyl Derivatives Targeting Folate Receptor-Positive Tumors for Boron Neutron Capture Therapy

Water-soluble pteroyl-closo-dodecaborate conjugates (PBCs 1–4), were developed as folate receptor (FRα) targeting boron carriers for boron neutron capture therapy (BNCT). PBCs 1–4 had adequately low cytotoxicity with IC(50) values in the range of 1~3 mM toward selected human cancer cells, low enough...

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Detalles Bibliográficos
Autores principales: Nakagawa, Fumiko, Kawashima, Hidehisa, Morita, Taiki, Nakamura, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407413/
https://www.ncbi.nlm.nih.gov/pubmed/32635272
http://dx.doi.org/10.3390/cells9071615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407413/
https://www.ncbi.nlm.nih.gov/pubmed/32635272
http://dx.doi.org/10.3390/cells9071615

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