In Vitro and In Vivo Assessment of PEGylated PEI for Anti-IL-8/CxCL-1 siRNA Delivery to the Lungs

Inhalation offers a means of rapid, local delivery of siRNA to treat a range of autoimmune or inflammatory respiratory conditions. This work investigated the potential of a linear 10 kDa Poly(ethylene glycol) (PEG)-modified 25 kDa branched polyethyleneimine (PEI) (PEI-LPEG) to effectively deliver si...

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Detalles Bibliográficos
Autores principales: Hibbitts, Alan J., Ramsey, Joanne M., Barlow, James, MacLoughlin, Ronan, Cryan, Sally-Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407419/
https://www.ncbi.nlm.nih.gov/pubmed/32605011
http://dx.doi.org/10.3390/nano10071248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407419/
https://www.ncbi.nlm.nih.gov/pubmed/32605011
http://dx.doi.org/10.3390/nano10071248

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