Repeated Administration of Clinical Doses of Tramadol and Tapentadol Causes Hepato- and Nephrotoxic Effects in Wistar Rats

Tramadol and tapentadol are fully synthetic and extensively used analgesic opioids, presenting enhanced therapeutic and safety profiles as compared with their peers. However, reports of adverse reactions, intoxications and fatalities have been increasing. Information regarding the molecular, biochem...

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Detalles Bibliográficos
Autores principales: Barbosa, Joana, Faria, Juliana, Garcez, Fernanda, Leal, Sandra, Afonso, Luís Pedro, Nascimento, Ana Vanessa, Moreira, Roxana, Queirós, Odília, Carvalho, Félix, Dinis-Oliveira, Ricardo Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407499/
https://www.ncbi.nlm.nih.gov/pubmed/32664348
http://dx.doi.org/10.3390/ph13070149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407499/
https://www.ncbi.nlm.nih.gov/pubmed/32664348
http://dx.doi.org/10.3390/ph13070149

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