Formulation of Sustained Release Hydrophilic Matrix Tablets of Tolcapone with the Application of Sedem Diagram: Influence of Tolcapone’s Particle Size on Sustained Release

Hydrophilic matrix tablets are a type of sustained release dosage form characterized by distributing a drug in a matrix that is usually polymeric. Tolcapone is a drug that inhibits the enzyme catechol-O-methyl transferase. In recent years, it has been shown that tolcapone is a potent inhibitor of th...

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Detalles Bibliográficos
Autores principales: Nardi-Ricart, Anna, Nofrerias-Roig, Isaac, Suñé-Pou, Marc, Pérez-Lozano, Pilar, Miñarro-Carmona, Montse, García-Montoya, Encarna, Ticó-Grau, Josep R., Insa Boronat, Raul, Suñé-Negre, Josep M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407504/
https://www.ncbi.nlm.nih.gov/pubmed/32708961
http://dx.doi.org/10.3390/pharmaceutics12070674

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407504/
https://www.ncbi.nlm.nih.gov/pubmed/32708961
http://dx.doi.org/10.3390/pharmaceutics12070674

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