Regulation of Error-Prone DNA Double-Strand Break Repair and Its Impact on Genome Evolution

Double-strand breaks are one of the most deleterious DNA lesions. Their repair via error-prone mechanisms can promote mutagenesis, loss of genetic information, and deregulation of the genome. These detrimental outcomes are significant drivers of human diseases, including many cancers. Mutagenic doub...

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Detalles Bibliográficos
Autores principales: Hanscom, Terrence, McVey, Mitch
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407515/
https://www.ncbi.nlm.nih.gov/pubmed/32660124
http://dx.doi.org/10.3390/cells9071657

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407515/
https://www.ncbi.nlm.nih.gov/pubmed/32660124
http://dx.doi.org/10.3390/cells9071657

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