Cargando…
Regulation of Error-Prone DNA Double-Strand Break Repair and Its Impact on Genome Evolution
Double-strand breaks are one of the most deleterious DNA lesions. Their repair via error-prone mechanisms can promote mutagenesis, loss of genetic information, and deregulation of the genome. These detrimental outcomes are significant drivers of human diseases, including many cancers. Mutagenic doub...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407515/ https://www.ncbi.nlm.nih.gov/pubmed/32660124 http://dx.doi.org/10.3390/cells9071657 |