Human Serum Albumin-Inspired Glycopeptide-Based Multifunctional Inhibitor of Amyloid-β Toxicity

[Image: see text] In Alzheimer’s disease (AD), insoluble Aβ42 peptide fragments self-aggregate and form oligomers and fibrils in the brain, causing neurotoxicity. Further, the presence of redox-active metal ions such as Cu(2+) enhances the aggregation process through chelation with these Aβ42 aggreg...

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Detalles Bibliográficos
Autores principales: Roy, Rajsekhar, Pradhan, Krishnangsu, Khan, Juhee, Das, Gaurav, Mukherjee, Nabanita, Das, Durba, Ghosh, Surajit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407538/
https://www.ncbi.nlm.nih.gov/pubmed/32775865
http://dx.doi.org/10.1021/acsomega.0c01028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407538/
https://www.ncbi.nlm.nih.gov/pubmed/32775865
http://dx.doi.org/10.1021/acsomega.0c01028

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