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2D-QSAR Modeling and Molecular Docking Studies on 1H-Pyrazole-1-carbothioamide Derivatives as EGFR Kinase Inhibitors

[Image: see text] Epidermal growth factor receptor (EGFR) kinase has been commonly associated with cancers such as lung, ovarian, hormone-refractory prostate, metastatic colorectal, glioblastoma, pancreatic, and breast cancers. A series of 1H-pyrazole-1-carbothioamide derivatives and their EGFR inhi...

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Detalles Bibliográficos
Autores principales: Hajalsiddig, Tawassl T. H., Osman, Abu Baker M., Saeed, Ahmed E. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407542/
https://www.ncbi.nlm.nih.gov/pubmed/32775868
http://dx.doi.org/10.1021/acsomega.0c01323