Cargando…
2D-QSAR Modeling and Molecular Docking Studies on 1H-Pyrazole-1-carbothioamide Derivatives as EGFR Kinase Inhibitors
[Image: see text] Epidermal growth factor receptor (EGFR) kinase has been commonly associated with cancers such as lung, ovarian, hormone-refractory prostate, metastatic colorectal, glioblastoma, pancreatic, and breast cancers. A series of 1H-pyrazole-1-carbothioamide derivatives and their EGFR inhi...
Autores principales: | Hajalsiddig, Tawassl T. H., Osman, Abu Baker M., Saeed, Ahmed E. M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2020
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407542/ https://www.ncbi.nlm.nih.gov/pubmed/32775868 http://dx.doi.org/10.1021/acsomega.0c01323 |
Ejemplares similares
-
3D-QSAR and Molecular Docking Studies on Fused Pyrazoles as p38α Mitogen-Activated Protein Kinase Inhibitors
por: Lan, Ping, et al.
Publicado: (2010) -
Design and Synthesis of Aminopyrimidinyl Pyrazole Analogs as PLK1 Inhibitors Using Hybrid 3D-QSAR and Molecular Docking
por: Bhujbal, Swapnil P., et al.
Publicado: (2022) -
Molecular docking of 1H-pyrazole derivatives to receptor tyrosine kinase and protein kinase for screening potential inhibitors
por: Chandra,, et al.
Publicado: (2014) -
5-Hydroxy-3-methyl-5-phenyl-4,5-dihydro-1H-pyrazole-1-carbothioamide
por: Ganguly, Biplab, et al.
Publicado: (2011) -
3-Methyl-5-oxo-4-(2-phenylhydrazinylidene)-4,5-dihydro-1H-pyrazole-1-carbothioamide
por: Fun, Hoong-Kun, et al.
Publicado: (2011)