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Formulation Design, Statistical Optimization, and In Vitro Evaluation of a Naringenin Nanoemulsion to Enhance Apoptotic Activity in A549 Lung Cancer Cells

Naringenin (NAR), a flavonoid mainly found in citrus and grapefruits, has proven anti-cancer activities. However, the poor water solubility and low bioavailability of NAR limits its use as a therapeutic agent. The aim of this study was to develop and optimize stable naringenin nanoemulsions (NAR-NE)...

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Detalles Bibliográficos
Autores principales: Md, Shadab, Alhakamy, Nabil A., Aldawsari, Hibah M., Husain, Mohammad, Kotta, Sabna, Abdullah, Samaa T., A. Fahmy, Usama, Alfaleh, Mohamed A., Asfour, Hani Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407592/
https://www.ncbi.nlm.nih.gov/pubmed/32679917
http://dx.doi.org/10.3390/ph13070152