Development of a Gene Delivery System of Oligonucleotides for Fibroses by Targeting Cell-Surface Vimentin-Expressing Cells with N-Acetylglucosamine-Bearing Polymer-Conjugated Polyethyleneimine

Targeting myofibroblasts and activated stellate cells in lesion sites of fibrotic tissues is an important approach to treat fibroses. Herein, we focused on targeting the cytoskeletal proteins vimentin, which are reportedly highly expressed on the surface of these cells and have N-acetylglucosamine (...

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Detalles Bibliográficos
Autores principales: Song, Inu, Ise, Hirohiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407634/
https://www.ncbi.nlm.nih.gov/pubmed/32645972
http://dx.doi.org/10.3390/polym12071508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407634/
https://www.ncbi.nlm.nih.gov/pubmed/32645972
http://dx.doi.org/10.3390/polym12071508

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