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Red Blood Cell Peroxynitrite Causes Endothelial Dysfunction in Type 2 Diabetes Mellitus via Arginase

We recently showed that red blood cells (RBCs) from patients with type 2 diabetes mellitus (T2DM-RBCs) induce endothelial dysfunction through a mechanism involving arginase I and reactive oxygen species. Peroxynitrite is known to activate arginase in endothelial cells. Whether peroxynitrite regulate...

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Detalles Bibliográficos
Autores principales: Mahdi, Ali, Tengbom, John, Alvarsson, Michael, Wernly, Bernhard, Zhou, Zhichao, Pernow, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407649/
https://www.ncbi.nlm.nih.gov/pubmed/32708826
http://dx.doi.org/10.3390/cells9071712