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The COP9 Signalosome: A Multi-DUB Complex

The COP9 signalosome (CSN) is a signaling platform controlling the cellular ubiquitylation status. It determines the activity and remodeling of ~700 cullin-RING ubiquitin ligases (CRLs), which control more than 20% of all ubiquitylation events in cells and thereby influence virtually any cellular pa...

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Detalles Bibliográficos
Autores principales: Dubiel, Wolfgang, Chaithongyot, Supattra, Dubiel, Dawadschargal, Naumann, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407660/
https://www.ncbi.nlm.nih.gov/pubmed/32708147
http://dx.doi.org/10.3390/biom10071082