Disclosing the Interactome of Leukemogenic NUP98-HOXA9 and SET-NUP214 Fusion Proteins Using a Proteomic Approach

The interaction of oncogenes with cellular proteins is a major determinant of cellular transformation. The NUP98-HOXA9 and SET-NUP214 chimeras result from recurrent chromosomal translocations in acute leukemia. Functionally, the two fusion proteins inhibit nuclear export and interact with epigenetic...

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Detalles Bibliográficos
Autores principales: Mendes, Adélia, Jühlen, Ramona, Bousbata, Sabrina, Fahrenkrog, Birthe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407662/
https://www.ncbi.nlm.nih.gov/pubmed/32664447
http://dx.doi.org/10.3390/cells9071666

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407662/
https://www.ncbi.nlm.nih.gov/pubmed/32664447
http://dx.doi.org/10.3390/cells9071666

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