T-Cell Gene Therapy in Cancer Immunotherapy: Why It Is No Longer Just CARs on The Road

T-cells have a natural ability to fight cancer cells in the tumour microenvironment. Due to thymic selection and tissue-driven immunomodulation, these cancer-fighting T-cells are generally low in number and exhausted. One way to overcome these issues is to genetically alter T-cells to improve their...

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Detalles Bibliográficos
Autores principales: Crowther, Michael D., Svane, Inge Marie, Met, Özcan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407663/
https://www.ncbi.nlm.nih.gov/pubmed/32630096
http://dx.doi.org/10.3390/cells9071588

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407663/
https://www.ncbi.nlm.nih.gov/pubmed/32630096
http://dx.doi.org/10.3390/cells9071588

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