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T-Cell Gene Therapy in Cancer Immunotherapy: Why It Is No Longer Just CARs on The Road
T-cells have a natural ability to fight cancer cells in the tumour microenvironment. Due to thymic selection and tissue-driven immunomodulation, these cancer-fighting T-cells are generally low in number and exhausted. One way to overcome these issues is to genetically alter T-cells to improve their...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407663/ https://www.ncbi.nlm.nih.gov/pubmed/32630096 http://dx.doi.org/10.3390/cells9071588 |