Blockade of 67-kDa Laminin Receptor Facilitates AQP4 Down-Regulation and BBB Disruption via ERK1/2-and p38 MAPK-Mediated PI3K/AKT Activations

Recently, we have reported that dysfunctions of 67-kDa laminin receptor (67LR) induced by status epilepticus (SE, a prolonged seizure activity) and 67LR neutralization are involved in vasogenic edema formation, accompanied by the reduced aquaporin 4 (AQP4, an astroglial specific water channel) expre...

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Detalles Bibliográficos
Autores principales: Kim, Ji-Eun, Park, Hana, Lee, Ji-Eun, Kang, Tae-Cheon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407797/
https://www.ncbi.nlm.nih.gov/pubmed/32664509
http://dx.doi.org/10.3390/cells9071670

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407797/
https://www.ncbi.nlm.nih.gov/pubmed/32664509
http://dx.doi.org/10.3390/cells9071670

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