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ROS Mediate xCT-Dependent Cell Death in Human Breast Cancer Cells under Glucose Deprivation

xCT, also known as solute carrier family 7 member 11 (SLC7A11), the light chain of the cystine/glutamate antiporter, is positively correlated with cancer progression due to antioxidant function. During glucose deprivation, the overexpression of xCT does not protect cancer cells but instead promotes...

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Detalles Bibliográficos
Autores principales: Chen, Mei-Chun, Hsu, Li-Lin, Wang, Sheng-Fan, Hsu, Chih-Yi, Lee, Hsin-Chen, Tseng, Ling-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407809/
https://www.ncbi.nlm.nih.gov/pubmed/32630312
http://dx.doi.org/10.3390/cells9071598