Downregulation of Drp1 and Fis1 Inhibits Mitochondrial Fission and Prevents High Glucose-Induced Apoptosis in Retinal Endothelial Cells

Diabetic retinopathy is a prevalent microvascular complication characterized by apoptotic vascular cell loss in the retina. Previous studies have shown that high glucose (HG)-induced mitochondrial fragmentation plays a critical role in promoting retinal vascular cell apoptosis. Here, we investigated...

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Detalles Bibliográficos
Autores principales: Kim, Dongjoon, Sankaramoorthy, Aravind, Roy, Sayon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407825/
https://www.ncbi.nlm.nih.gov/pubmed/32664237
http://dx.doi.org/10.3390/cells9071662

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407825/
https://www.ncbi.nlm.nih.gov/pubmed/32664237
http://dx.doi.org/10.3390/cells9071662

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