Cargando…
Distinct Roles for RAB10 and RAB29 in Pathogenic LRRK2-Mediated Endolysosomal Trafficking Alterations
SUMMARY STATEMENT: Pathogenic LRRK2 expression causes endolysosomal trafficking alterations by impairing RAB10 function, and these alterations are rescued by RAB29 independent of its Golgi localization. ABSTRACT: Mutations in the gene encoding leucine-rich repeat kinase 2 (LRRK2) cause familial Park...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407826/ https://www.ncbi.nlm.nih.gov/pubmed/32709066 http://dx.doi.org/10.3390/cells9071719 |