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Ampicillin/Sulbactam Treatment Modulates NMDA Receptor NR2B Subunit and Attenuates Neuroinflammation and Alcohol Intake in Male High Alcohol Drinking Rats

Exposure to ethanol commonly manifests neuroinflammation. Beta (β)-lactam antibiotics attenuate ethanol drinking through upregulation of astroglial glutamate transporters, especially glutamate transporter-1 (GLT-1), in the mesocorticolimbic brain regions, including the nucleus accumbens (Acb). Howev...

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Detalles Bibliográficos
Autores principales: Alasmari, Fawaz, Alhaddad, Hasan, Wong, Woonyen, Bell, Richard L., Sari, Youssef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407831/
https://www.ncbi.nlm.nih.gov/pubmed/32664441
http://dx.doi.org/10.3390/biom10071030