A Mixed-Surface Polyamidoamine Dendrimer for In Vitro and In Vivo Delivery of Large Plasmids

Drug delivery to the brain is highly hindered by the presence of the blood–brain barrier (BBB), which prevents the entry of many potential drugs/biomolecules into the brain. One of the current strategies to achieve gene therapy for neurodegenerative diseases involves direct injection of a viral vect...

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Detalles Bibliográficos
Autores principales: Srinageshwar, Bhairavi, Florendo, Maria, Clark, Brittany, Johnson, Kayla, Munro, Nikolas, Peruzzaro, Sarah, Antcliff, Aaron, Andrews, Melissa, Figacz, Alexander, Swanson, Douglas, Dunbar, Gary L., Sharma, Ajit, Rossignol, Julien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407876/
https://www.ncbi.nlm.nih.gov/pubmed/32635142
http://dx.doi.org/10.3390/pharmaceutics12070619

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407876/
https://www.ncbi.nlm.nih.gov/pubmed/32635142
http://dx.doi.org/10.3390/pharmaceutics12070619

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