A Novel C1-Esterase Inhibitor Oxygenator Coating Prevents FXII Activation in Human Blood

The limited hemocompatibility of currently used oxygenator membranes prevents long-term use of artificial lungs in patients with lung failure. To improve hemocompatibility, we developed a novel covalent C1-esterase inhibitor (C1-INH) coating. Besides complement inhibition, C1-INH also prevents FXII...

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Detalles Bibliográficos
Autores principales: Gerling, Katharina, Ölschläger, Sabrina, Avci-Adali, Meltem, Neumann, Bernd, Schweizer, Ernst, Schlensak, Christian, Wendel, Hans-Peter, Stoppelkamp, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407883/
https://www.ncbi.nlm.nih.gov/pubmed/32668719
http://dx.doi.org/10.3390/biom10071042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407883/
https://www.ncbi.nlm.nih.gov/pubmed/32668719
http://dx.doi.org/10.3390/biom10071042

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