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PTEN Protein Loss and Loss-of-Function Mutations in Gastric Cancers: The Relationship with Microsatellite Instability, EBV, HER2, and PD-L1 Expression

Inactivation of phosphatase and tensin homolog (PTEN) is caused by multiple mechanisms, and loss of PTEN activity is related to the progression of various cancers. In gastric cancer (GC), the relationship between the loss of PTEN protein expression and various genetic alterations remains unclear. Th...

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Detalles Bibliográficos
Autores principales: Kim, Binnari, Kang, So Young, Kim, Deokgeun, Heo, You Jeong, Kim, Kyoung-Mee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407887/
https://www.ncbi.nlm.nih.gov/pubmed/32610572
http://dx.doi.org/10.3390/cancers12071724