Probing the DNA Reactivity and the Anticancer Properties of a Novel Tubercidin-Pt(II) Complex

Herein, we reported on the synthesis of a novel Pt(II) neutral complex having as ligand the nucleoside tubercidin, a potent anti-tumor agent extracted from the bacterium Streptomyces Tubercidicus. In detail, the chelation of the metal by a diamine linker installed at C6 purine position of tubercidin...

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Detalles Bibliográficos
Autores principales: D’Errico, Stefano, Falanga, Andrea Patrizia, Capasso, Domenica, Di Gaetano, Sonia, Marzano, Maria, Terracciano, Monica, Roviello, Giovanni Nicola, Piccialli, Gennaro, Oliviero, Giorgia, Borbone, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407906/
https://www.ncbi.nlm.nih.gov/pubmed/32635488
http://dx.doi.org/10.3390/pharmaceutics12070627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407906/
https://www.ncbi.nlm.nih.gov/pubmed/32635488
http://dx.doi.org/10.3390/pharmaceutics12070627

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