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Probing the DNA Reactivity and the Anticancer Properties of a Novel Tubercidin-Pt(II) Complex
Herein, we reported on the synthesis of a novel Pt(II) neutral complex having as ligand the nucleoside tubercidin, a potent anti-tumor agent extracted from the bacterium Streptomyces Tubercidicus. In detail, the chelation of the metal by a diamine linker installed at C6 purine position of tubercidin...
Autores principales: | D’Errico, Stefano, Falanga, Andrea Patrizia, Capasso, Domenica, Di Gaetano, Sonia, Marzano, Maria, Terracciano, Monica, Roviello, Giovanni Nicola, Piccialli, Gennaro, Oliviero, Giorgia, Borbone, Nicola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407906/ https://www.ncbi.nlm.nih.gov/pubmed/32635488 http://dx.doi.org/10.3390/pharmaceutics12070627 |
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