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Cell-Adhesion Properties of β-Subunits in the Regulation of Cardiomyocyte Sodium Channels

Voltage-gated sodium (Nav) channels drive the rising phase of the action potential, essential for electrical signalling in nerves and muscles. The Nav channel α-subunit contains the ion-selective pore. In the cardiomyocyte, Nav1.5 is the main Nav channel α-subunit isoform, with a smaller expression...

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Detalles Bibliográficos
Autores principales: Salvage, Samantha C., Huang, Christopher L.-H., Jackson, Antony P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407995/
https://www.ncbi.nlm.nih.gov/pubmed/32630316
http://dx.doi.org/10.3390/biom10070989