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SETD1A Promotes Proliferation of Castration-Resistant Prostate Cancer Cells via FOXM1 Transcription

Androgen deprivation therapy eventually leads to the development of castration-resistant prostate cancer (CRPC). Here, we demonstrate for the first time that the histone H3K4 methyltransferase SETD1A is a major regulator for the proliferation of metastatic CRPC (mCRPC). The expression of SETD1A was...

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Detalles Bibliográficos
Autores principales: Yang, Liu, Jin, Mingli, Park, Sung Jean, Seo, Seung-Yong, Jeong, Kwang Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407996/
https://www.ncbi.nlm.nih.gov/pubmed/32629770
http://dx.doi.org/10.3390/cancers12071736