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SETD1A Promotes Proliferation of Castration-Resistant Prostate Cancer Cells via FOXM1 Transcription
Androgen deprivation therapy eventually leads to the development of castration-resistant prostate cancer (CRPC). Here, we demonstrate for the first time that the histone H3K4 methyltransferase SETD1A is a major regulator for the proliferation of metastatic CRPC (mCRPC). The expression of SETD1A was...
Autores principales: | Yang, Liu, Jin, Mingli, Park, Sung Jean, Seo, Seung-Yong, Jeong, Kwang Won |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7407996/ https://www.ncbi.nlm.nih.gov/pubmed/32629770 http://dx.doi.org/10.3390/cancers12071736 |
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