PTPN2 Deficiency Enhances Programmed T Cell Expansion and Survival Capacity of Activated T Cells

Manipulating molecules that impact T cell receptor (TCR) or cytokine signaling, such as the protein tyrosine phosphatase non-receptor type 2 (PTPN2), has significant potential for advancing T cell-based immunotherapies. Nonetheless, it remains unclear how PTPN2 impacts the activation, survival, and...

Descripción completa

Detalles Bibliográficos
Autores principales: Flosbach, Markus, Oberle, Susanne G., Scherer, Stefanie, Zecha, Jana, von Hoesslin, Madlaina, Wiede, Florian, Chennupati, Vijaykumar, Cullen, Jolie G., List, Markus, Pauling, Josch K., Baumbach, Jan, Kuster, Bernhard, Tiganis, Tony, Zehn, Dietmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408006/
https://www.ncbi.nlm.nih.gov/pubmed/32726622
http://dx.doi.org/10.1016/j.celrep.2020.107957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408006/
https://www.ncbi.nlm.nih.gov/pubmed/32726622
http://dx.doi.org/10.1016/j.celrep.2020.107957

Ejemplares similares