An Apoptotic Caspase Network Safeguards Cell Death Induction in Pyroptotic Macrophages

Pyroptosis has emerged as a key mechanism by which inflammasomes promote host defense against microbial pathogens and sterile inflammation. Gasdermin D (GSDMD)-mediated cell lysis is a hallmark of pyroptosis, but our understanding of cell death signaling during pyroptosis is fragmented. Here, we sho...

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Detalles Bibliográficos
Autores principales: de Vasconcelos, Nathalia Moraes, Van Opdenbosch, Nina, Van Gorp, Hanne, Martín-Pérez, Rosa, Zecchin, Annalisa, Vandenabeele, Peter, Lamkanfi, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408007/
https://www.ncbi.nlm.nih.gov/pubmed/32726624
http://dx.doi.org/10.1016/j.celrep.2020.107959

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408007/
https://www.ncbi.nlm.nih.gov/pubmed/32726624
http://dx.doi.org/10.1016/j.celrep.2020.107959

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