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An Apoptotic Caspase Network Safeguards Cell Death Induction in Pyroptotic Macrophages
Pyroptosis has emerged as a key mechanism by which inflammasomes promote host defense against microbial pathogens and sterile inflammation. Gasdermin D (GSDMD)-mediated cell lysis is a hallmark of pyroptosis, but our understanding of cell death signaling during pyroptosis is fragmented. Here, we sho...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408007/ https://www.ncbi.nlm.nih.gov/pubmed/32726624 http://dx.doi.org/10.1016/j.celrep.2020.107959 |