Cargando…

N-Alkylisatin-Loaded Liposomes Target the Urokinase Plasminogen Activator System in Breast Cancer

The urokinase plasminogen activator and its receptor (uPA/uPAR) are biomarkers for metastasis, especially in triple-negative breast cancer. We prepared anti-mitotic N-alkylisatin (N-AI)-loaded liposomes functionalized with the uPA/uPAR targeting ligand, plasminogen activator inhibitor type 2 (PAI-2/...

Descripción completa

Detalles Bibliográficos
Autores principales: Belfiore, Lisa, Saunders, Darren N., Ranson, Marie, Vine, Kara L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408009/
https://www.ncbi.nlm.nih.gov/pubmed/32645963
http://dx.doi.org/10.3390/pharmaceutics12070641