KLF4 Acts as a wt-CFTR Suppressor through an AKT-Mediated Pathway

Cystic Fibrosis (CF) is caused by >2000 mutations in the CF transmembrane conductance regulator (CFTR) gene, but one mutation—F508del—occurs in ~80% of patients worldwide. Besides its main function as an anion channel, the CFTR protein has been implicated in epithelial differentiation, tissue reg...

Descripción completa

Detalles Bibliográficos
Autores principales: Sousa, Luis, Pankonien, Ines, Clarke, Luka A, Silva, Iris, Kunzelmann, Karl, Amaral, Margarida D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408019/
https://www.ncbi.nlm.nih.gov/pubmed/32630830
http://dx.doi.org/10.3390/cells9071607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408019/
https://www.ncbi.nlm.nih.gov/pubmed/32630830
http://dx.doi.org/10.3390/cells9071607

Ejemplares similares