MHC Class I-Restricted TCR-Transgenic CD4(+) T Cells Against STEAP1 Mediate Local Tumor Control of Ewing Sarcoma In Vivo

In this study we report the functional comparison of T cell receptor (TCR)-engineered major histocompatibility complex (MHC) class I-restricted CD4(+) versus CD8(+) T cells targeting a peptide from six transmembrane epithelial antigen of the prostate 1 (STEAP1) in the context of HLA-A*02:01. STEAP1...

Descripción completa

Detalles Bibliográficos
Autores principales: Schober, Sebastian J., Thiede, Melanie, Gassmann, Hendrik, Prexler, Carolin, Xue, Busheng, Schirmer, David, Wohlleber, Dirk, Stein, Stefanie, Grünewald, Thomas G. P., Busch, Dirk H., Richter, Guenther H. S., Burdach, Stefan E. G., Thiel, Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408051/
https://www.ncbi.nlm.nih.gov/pubmed/32610710
http://dx.doi.org/10.3390/cells9071581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408051/
https://www.ncbi.nlm.nih.gov/pubmed/32610710
http://dx.doi.org/10.3390/cells9071581

Ejemplares similares