A Novel Combination Treatment with Honokiol and Rapamycin Effectively Restricts c-Met-Induced Growth of Renal Cancer Cells, and also Inhibits the Expression of Tumor Cell PD-L1 Involved in Immune Escape

The mTOR inhibitor Rapamycin has tumor inhibitory properties; and it is also used as an immunosuppressive agent after organ transplantation. However, prolonged Rapamycin treatment re-activates Akt and can promote cancer growth. Honokiol is a natural compound with both anti-tumorigenic and anti-infla...

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Detalles Bibliográficos
Autores principales: Sabarwal, Akash, Chakraborty, Samik, Mahanta, Simran, Banerjee, Selina, Balan, Murugabaskar, Pal, Soumitro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408055/
https://www.ncbi.nlm.nih.gov/pubmed/32635337
http://dx.doi.org/10.3390/cancers12071782

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408055/
https://www.ncbi.nlm.nih.gov/pubmed/32635337
http://dx.doi.org/10.3390/cancers12071782

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