CMH-Small Molecule Docks into SIRT1, Elicits Human IPF-Lung Fibroblast Cell Death, Inhibits Ku70-deacetylation, FLIP and Experimental Pulmonary Fibrosis

Regenerative capacity in vital organs is limited by fibrosis propensity. Idiopathic pulmonary fibrosis (IPF), a progressive lung disease linked with aging, is a classic example. In this study, we show that in flow cytometry, immunoblots (IB) and in lung sections, FLIP levels can be regulated, in viv...

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Detalles Bibliográficos
Autores principales: Konikov-Rozenman, Jenya, Breuer, Raphael, Kaminski, Naftali, Wallach-Dayan, Shulamit B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408087/
https://www.ncbi.nlm.nih.gov/pubmed/32630842
http://dx.doi.org/10.3390/biom10070997

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408087/
https://www.ncbi.nlm.nih.gov/pubmed/32630842
http://dx.doi.org/10.3390/biom10070997

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