Antiproliferative Effect of 4-Methylumbelliferone in Epithelial Ovarian Cancer Cells Is Mediated by Disruption of Intracellular Homeostasis and Regulation of PI3K/AKT and MAPK Signaling

Ovarian cancer has a high mortality rate and high resistance to chemotherapy. Thus, many studies are currently assessing the ability of natural products to induce ovarian cancer cell death. A coumarin derivative, 4-methylumbelliferone (4-MU), has been reported to have anti-cancer effects on various...

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Detalles Bibliográficos
Autores principales: An, Garam, Park, Sunwoo, Lee, Minkyoung, Lim, Whasun, Song, Gwonhwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408106/
https://www.ncbi.nlm.nih.gov/pubmed/32645961
http://dx.doi.org/10.3390/pharmaceutics12070640

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408106/
https://www.ncbi.nlm.nih.gov/pubmed/32645961
http://dx.doi.org/10.3390/pharmaceutics12070640

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