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On the Risks of Phylogeny-Based Strain Prioritization for Drug Discovery: Streptomyces lunaelactis as a Case Study

Strain prioritization for drug discovery aims at excluding redundant strains of a collection in order to limit the repetitive identification of the same molecules. In this work, we wanted to estimate what can be unexploited in terms of the amount, diversity, and novelty of compounds if the search is...

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Detalles Bibliográficos
Autores principales: Martinet, Loïc, Naômé, Aymeric, Baiwir, Dominique, De Pauw, Edwin, Mazzucchelli, Gabriel, Rigali, Sébastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408125/
https://www.ncbi.nlm.nih.gov/pubmed/32664387
http://dx.doi.org/10.3390/biom10071027