Cargando…

Mesothelin-Targeted Recombinant Immunotoxins for Solid Tumors

Mesothelin (MSLN) is a cell surface glycoprotein normally expressed only on serosal surfaces, and not found in the parenchyma of vital organs. Many solid tumors also express MSLN, including mesothelioma and pancreatic adenocarcinoma. Due to this favorable expression profile, MSLN represents a viable...

Descripción completa

Detalles Bibliográficos
Autores principales: Hagerty, Brendan L., Pegna, Guillaume J., Xu, Jian, Tai, Chin-Hsien, Alewine, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408136/
https://www.ncbi.nlm.nih.gov/pubmed/32605175
http://dx.doi.org/10.3390/biom10070973