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Mesothelin-Targeted Recombinant Immunotoxins for Solid Tumors
Mesothelin (MSLN) is a cell surface glycoprotein normally expressed only on serosal surfaces, and not found in the parenchyma of vital organs. Many solid tumors also express MSLN, including mesothelioma and pancreatic adenocarcinoma. Due to this favorable expression profile, MSLN represents a viable...
Autores principales: | Hagerty, Brendan L., Pegna, Guillaume J., Xu, Jian, Tai, Chin-Hsien, Alewine, Christine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408136/ https://www.ncbi.nlm.nih.gov/pubmed/32605175 http://dx.doi.org/10.3390/biom10070973 |
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