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Approaches to Dose Finding in Neonates, Illustrating the Variability between Neonatal Drug Development Programs

Drug dosing in neonates should be based on integrated knowledge concerning the disease to be treated, the physiological characteristics of the neonate, and the pharmacokinetics (PK) and pharmacodynamics (PD) of a given drug. It is critically important that all sources of information be leveraged to...

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Detalles Bibliográficos
Autores principales: Van den Anker, John N., McCune, Susan, Annaert, Pieter, Baer, Gerri R., Mulugeta, Yeruk, Abdelrahman, Ramy, Wu, Kunyi, Krudys, Kevin M., Fisher, Jeffrey, Slikker, William, Chen, Connie, Burckart, Gilbert J., Allegaert, Karel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408157/
https://www.ncbi.nlm.nih.gov/pubmed/32698409
http://dx.doi.org/10.3390/pharmaceutics12070685